As a direct sequel to the 2020 Speed Duel: Battle City Box, a second Speed Duel Box will be released in February 2022 themed around Yu-Gi-Oh! GX.

The point of a Speed Duel Box is to provide an easy way for up to eight players to instantly jump into the action with decks themed around popular archetypes and characters from the Yu-Gi-Oh! anime and cardgame. Each box includes around 200 cards that are pre-packaged in a format similar to Structure Decks, with some bonus cards that vary between boxes.